$5,900.00 – $6,400.00
The MazeEngineers automated conditioned place preference system features two identical acrylic compartments linked by a central corridor, with the option to select your preferred color. Each compartment operates autonomously, providing independent control over animal location detection, lighting, and shock settings. The system includes removable acrylic panels, enabling customization of contexts during the CPP experiment. Optional automated doors can be added to your configuration. The entire setup also includes a removable top made of clear acrylic.
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Mouse 3 Chamber CPP |
Three chambers |
Contextual plates: White; black; striped |
2 dual control shock grids |
2 dual control lights |
(Optional addon) Sound |
Rat 3 Chamber CPP |
Three chambers |
Contextual plates: White; black; striped |
2 dual control shock grids |
2 dual control lights |
(Optional addon) Sound |
The Automated Conditioned Place Preference Apparatus is an advanced adaptation of the traditional Conditioned Place Preference Test. This automated version enhances the standard setup with features such as infrared detection, separate controls for lighting, and independent shock grid management. The apparatus includes two equally sized acrylic compartments linked by a central corridor.
The Conditioned Place Preference Test is used to evaluate the rewarding and aversive effects of substances. Initially, rodentsā preference for one compartment over the other is assessed by recording the time spent in each compartment during a pre-conditioning phase. In the subsequent conditioning phase, the preferred compartment is associated with a control substance (e.g., saline), while the non-preferred compartment is paired with the drug. Rodents receive injections of either saline or the drug and are then confined to the corresponding compartment on alternate days. The post-conditioning phase, which mirrors the pre-conditioning phase but without drug or saline injections, assesses whether the rodentās initial compartment preference has shifted due to conditioning. Each compartment features unique cues, helping animals link these cues with the reinforcer (Prus, James, & Rosecrans, 2009).
The Automated Conditioned Place Preference Apparatus is designed with independently controlled lights in both chambers to act as cues. The compartments can be equipped with interchangeable acrylic plates in white, black, or striped patterns to provide varied contexts. Additionally, each compartment includes a removable shock grid for administering shocks, which can be used as a form of reinforcement.
The Automated Conditioned Place Preference Apparatus features three acrylic compartments: two larger experimental chambers connected by a smaller central corridor. A clear, removable acrylic cover encases all three compartments.
The system includes interchangeable contextual plates in white, black, and striped patterns, along with two sets of independently controlled lights and shock grids. The removable shock grids can deliver currents ranging from 0.1 to 4.0 mA in 0.1 mA increments. Advanced infrared sensor mechanisms between the compartments enable automated detection and counting, complementing video tracking systems like the Noldus EthoVision XT. Each chamber operates autonomously, managing its own light, shock, and animal location detection functions.
Additionally, Conduct Science provides optional speakers for sound cues that can be installed in the experimental chambers. Automated guillotine doors can also be added upon request.
Thoroughly clean all compartments and bottom trays with isopropyl alcohol (70%) and dry them with a paper towel before each trial.
The following is a sample protocol to study conditioned place preference in rodents:
The following parameters can be observed using the Automated Conditioned Place Preference Apparatus:
| Chamber | Mouse 3 Chamber CPP, Rat 3 Chamber CPP |
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DISCLAIMER: ConductScience and affiliate products are NOT designed for human consumption, testing, or clinical utilization. They are designed for pre-clinical utilization only. Customers purchasing apparatus for the purposes of scientific research or veterinary care affirm adherence to applicable regulatory bodies for the country in which their research or care is conducted.
